Schedule II Opioids (e.g., fentanyl, oxycodone, morphine)

Schedule II opioids are prescription drugs with a high potential for abuse that can lead to severe physical or psychological dependence, yet they are recognized for legitimate medical use in pain management. Examples include fentanyl, oxycodone and morphine, which are subject to strict prescribing controls, limited refills, and rigorous record-keeping requirements under DEA regulations.