Diseases of neuromuscular junction or muscle

**Definition:** Diseases resulting from destruction or malfunction of the neuromuscular junction, a chemical synapse formed between the end of the motor nerve terminal and the voluntary muscle. Pathology can occur at the presynaptic or postsynaptic membrane and leads to dysfunction of neuromuscular transmission. Common diseases of this category include Myasthenia Gravis and Lambert Eaton Myasthenic Syndrome.