World Of Taxonomy
D000071177Level 7

Signaling Lymphocytic Activation Molecule Family Member 1

**Definition:** A 70-kDa SLAM family receptor that consists of an extracellular IMMUNOGLOBULIN-LIKE DOMAIN and an IMMUNOGLOBULIN C2-SET DOMAIN. It is expressed primarily by THYMOCYTES and activated T-LYMPHOCYTES, as well as by MACROPHAGES and DENDRITIC CELLS. It binds SLAMF1 receptors on other cells to mediate T-cell maturation and proliferation. It is also a receptor for the MEASLES VIRUS.

**Tree numbers:** - D09.400.430.890.736.500 - D12.776.395.550.736.500 - D12.776.543.550.746.500 - D12.776.543.750.705.970.500

**Synonyms:** - CDw150 Protein - SLAM Protein - SLAMF1 Protein - SLAM Receptor - SLAMF1 Receptor - CD150 Antigen

GET/api/v1/systems/mesh/nodes/D000071177
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