Death Domain

**Definition:** A conserved protein interaction domain of the death domain superfamily that is structurally similar to the DEATH EFFECTOR DOMAIN and CASPASE RECRUITMENT DOMAIN. Death domains bind each other to form oligomers and occur on DEATH DOMAIN RECEPTORS, where they are required for APOPTOSIS signaling and non-apoptotic functions.

**Tree numbers:** - G02.111.570.820.709.275.750.500.395.500

**Synonyms:** - Death Domains