Death Effector Domain

**Definition:** A homotypic protein interaction module of the death domain superfamily that is composed of a bundle of six alpha-helices. The death effector domain shares sequence and structural similarities with the DEATH DOMAIN and CASPASE RECRUITMENT DOMAIN. It occurs in many proteins with essential functions in APOPTOSIS.

**Tree numbers:** - G02.111.570.820.709.275.750.500.395.750

**Synonyms:** - DED Domain