APOBEC Deaminases

**Definition:** A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.

**Tree numbers:** - D08.811.277.151.486.250.500

**Synonyms:** - Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides - AID-APOBEC Deaminases - APOBEC Enzymes - APOBEC Family Proteins