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D000071679Level 6

Glycogen Synthase Kinase 3 beta

**Definition:** A glycogen synthase kinase-3 type enzyme that functions in ENERGY METABOLISM; EMBRYONIC DEVELOPMENT; and NEUROGENESIS. It is also involved in PROTEIN BIOSYNTHESIS and regulates cell growth and proliferation as a component of the WNT SIGNALING PATHWAY and other signaling pathways. Certain polymorphisms in the GSK3B gene have been associated with PARKINSON DISEASE; ALZHEIMER DISEASE; and BIPOLAR DISORDER.

**Tree numbers:** - D05.500.117.875.500 - D08.811.913.696.620.682.700.429.500.500 - D08.811.913.696.620.682.700.646.625.500 - D12.776.476.081.875.500 - D12.776.476.563.429.500.500 - D12.776.476.563.646.625.500

**Synonyms:** - GSK3B Protein - GSK-3beta - GSK3beta

GET/api/v1/systems/mesh/nodes/D000071679
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