Patched-2 Receptor

**Definition:** A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; BASAL CELL CARCINOMA; and MEDULLOBLASTOMA.

**Tree numbers:** - D12.776.543.750.058.750 - D12.776.624.776.633.750

**Synonyms:** - Patched Homolog-2 - Patched Receptor-2 - Patched-2 Protein - PTCH2 Protein