Patched Receptors

**Definition:** A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.

**Tree numbers:** - D12.776.543.750.058 - D12.776.624.776.633

**Synonyms:** - Patched Receptor - Patched Protein - Patched Sonic Hedgehog Receptors