Smoothened Receptor

**Definition:** A frizzled-like, G-protein-coupled receptor that associates with PATCHED RECEPTORS to transduce signals from HEDGEHOG PROTEINS and initiate hedgehog signaling to ZINC FINGER PROTEIN GLI1. It may normally inhibit signaling in the absence of SONIC HEDGEHOG PROTEIN binding to PATCHED RECEPTOR-1.

**Tree numbers:** - D12.776.543.750.695.017.500 - D12.776.543.750.850.500.500

**Synonyms:** - Smoothened Receptors - Smoothened Protein