Frizzled Receptors

**Definition:** A family of seven-pass transmembrane cell-surface proteins that combines with LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 or LOW DENSITY LIPROTEIN RECEPTOR-RELATED PROTEIN-5 to form receptors for WNT PROTEINS. Frizzled receptors often couple with HETEROTRIMERIC G PROTEINS and regulate the WNT SIGNALING PATHWAY.

**Tree numbers:** - D12.776.543.750.695.017 - D12.776.543.750.850.500

**Synonyms:** - Frizzled Proteins - Frizzled Receptor - Receptors, Frizzled