Ku Autoantigen

**Definition:** An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.

**Tree numbers:** - D08.811.277.040.025.159.155 - D08.811.399.340.155 - D12.776.157.687.493 - D12.776.260.525 - D12.776.660.625.625 - D12.776.660.720.493 - D23.050.290.625

**Synonyms:** - Ku Antigen - G22P1 Antigen - Ku Heterodimer - Ku Protein