DNA Helicases

**Definition:** Proteins that catalyze the unwinding of duplex DNA during replication by binding cooperatively to single-stranded regions of DNA or to short regions of duplex DNA that are undergoing transient opening. In addition, DNA helicases are DNA-dependent ATPases that harness the free energy of ATP hydrolysis to translocate DNA strands.

**Tree numbers:** - D08.811.277.040.025.159 - D08.811.399.340

**Synonyms:** - DNA Helicase - DNA Unwinding Proteins - DNA Unwinding Protein