ATP Binding Cassette Transporter, Subfamily A

**Definition:** A large, highly conserved, subfamily of ATP binding cassette transporters structurally characterized by a membrane-spanning domain composed of six ALPHA-HELICES, a large extracellular loop, nucleotide-binding domain, and a conserved cytoplasmic 80 amino acid sequence. In humans, it includes ABCA1(ATP BINDING CASSETTE TRANSPORTER 1) through ABCA10, as well as ABCA12 and ABCA13.

**Tree numbers:** - D09.400.430.890.020.381 - D12.776.157.530.100.050 - D12.776.395.550.020.381 - D12.776.543.550.192.381 - D12.776.543.585.100.190

**Synonyms:** - ATP Binding Cassette Transporter, Sub-Family A - ABCA Transporters