ATP Binding Cassette Transporter 1

**Definition:** A superfamily of integral ATP-binding cassette membrane proteins whose expression pattern is consistent with a role in lipid (cholesterol) efflux. It is implicated in TANGIER DISEASE, characterized by accumulation of cholesteryl ester in various tissues.

**Tree numbers:** - D09.400.430.890.020.381.500 - D12.776.157.530.100.050.500 - D12.776.395.550.020.381.500 - D12.776.543.550.192.381.500 - D12.776.543.585.100.190.500

**Synonyms:** - Cholesterol-Efflux Regulatory Protein - CERP Protein - ATP-Binding Cassette Sub-Family A Member 1 - ATP Binding Cassette Transporter, Subfamily A, Member 1 - ABCA1 Protein