Aldo-Keto Reductase Family 1 Member C3

**Definition:** Aldo-keto reductase that functions as a bi-directional 17 BETA, 20 ALPHA-HYDROXYSTEROID DEHYDROGENASE. It catalyzes the reduction of PROSTAGLANDIN D2 and PROSTAGLANDIN H2, as well as the oxidation of 9alpha,11beta-PGF2 to prostaglandin D2. It can also interconvert estrogens, ANDROGENS; and PROGESTINS between their active forms and inactive metabolites.

**Tree numbers:** - D08.811.682.047.150.700.156.875 - D08.811.682.047.436.375.140 - D08.811.682.047.820.284.937 - D08.811.682.047.820.375.500

**Synonyms:** - Dihydrodiol Dehydrogenase 3 - 17-beta-Hydroxysteroid Dehydrogenase Type 5 - AKR1C3 Protein