World Of Taxonomy
D000076242Level 5

mTOR Associated Protein, LST8 Homolog

**Definition:** An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and mTORC2 COMPLEX. It interacts directly with mTOR to enhance its kinase activity and stabilizes the mTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of mTOR activity.

**Tree numbers:** - D05.500.337.250 - D08.811.913.696.620.682.700.931.500.250 - D12.644.360.024.310 - D12.776.157.057.073 - D12.776.476.024.389 - D12.776.476.563.931.500.250

**Synonyms:** - GBetaL Protein - mLST8 Protein - G protein beta Subunit-like Polypeptide

GET/api/v1/systems/mesh/nodes/D000076242
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