Cilastatin, Imipenem Drug Combination

**Definition:** Combination of imipenem and cilastatin that is used in the treatment of bacterial infections; cilastatin inhibits renal dehydropeptidase I to prolong the half-life and increase the tissue penetration of imipenem, enhancing its efficacy as an anti-bacterial agent.

**Tree numbers:** - D02.065.589.099.124.300.500.500 - D02.455.426.392.368.533.200.500 - D03.633.100.300.124.300.500.500 - D10.251.355.325.200.500 - D26.310.356

**Synonyms:** - Imipenem - Cilastatin - Imipenem-Cilastatin - Imipenem Cilastatin