D015378Level 8
Imipenem
**Definition:** Semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains. It is stable to beta-lactamases. Clinical studies have demonstrated high efficacy in the treatment of infections of various body systems. Its effectiveness is enhanced when it is administered in combination with CILASTATIN, a renal dipeptidase inhibitor.
**Tree numbers:** - D02.065.589.099.124.300.500 - D03.633.100.300.124.300.500
**Synonyms:** - Imipemide - N-Formimidoylthienamycin
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