p300-CBP-Associated Factor

**Definition:** A p300-CBP transcription factor with intrinsic HISTONE ACETYLASE activity that functions to promote TRANSCRIPTIONAL ACTIVATION. Among its functions is suppression of the CELL CYCLE where it competes with ADENOVIRUS E1A PROTEINS.

**Tree numbers:** - D08.811.913.050.134.415.500.575.601 - D12.776.930.680.601

**Synonyms:** - Histone Acetylase p300 - p300 Acetyltransferase - p300-CREB-Binding Protein-Associated Factor - PCAF Acetylase - PCAF Histone Acetylase