Immunoglobulin Variable Region

**Definition:** That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.

**Tree numbers:** - D12.644.541.500.650.500 - D12.776.124.486.485.680.650.500 - D12.776.124.486.485.797 - D12.776.124.790.651.680.650.500 - D12.776.124.790.651.797 - D12.776.377.715.548.680.650.500 - D12.776.377.715.548.797 - G02.111.570.060.425

**Synonyms:** - Variable Region, Immunoglobulin - Ig Variable Region - Immunoglobulin V - Variable Region, Ig