Complementarity Determining Regions

**Definition:** Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).

**Tree numbers:** - D12.644.541.500.650.500.180 - D12.776.124.486.485.680.650.500.180 - D12.776.124.486.485.797.180 - D12.776.124.790.651.680.650.500.180 - D12.776.124.790.651.797.180 - D12.776.377.715.548.680.650.500.180 - D12.776.377.715.548.797.180 - D12.776.543.750.705.816.824.300 - G02.111.570.060.425.160

**Synonyms:** - Complementarity Determining Region - Complementarity-Determining Region - Hypervariable Region, Immunoglobulin - Hypervariable Regions, Immunoglobulin