Familial Mediterranean Fever

**Definition:** A group of HEREDITARY AUTOINFLAMMATION DISEASES, characterized by recurrent fever, abdominal pain, headache, rash, PLEURISY; and ARTHRITIS. ORCHITIS; benign MENINGITIS; and AMYLOIDOSIS may also occur. Homozygous or compound heterozygous mutations in marenostrin gene encoding PYRIN result in autosomal recessive transmission; simple heterozygous, autosomal dominant form of the disease also exists with mutations in the same gene.

**Tree numbers:** - C16.320.382.625

**Synonyms:** - Periodic Peritonitis - Polyserositis, Familial Paroxysmal - Polyserositis, Recurrent - Recurrent Polyserositis - Wolff Periodic Disease - Wolff's Periodic Disease - Benign Paroxysmal Peritonitis - Familial Paroxysmal Polyserositis - Mediterranean Fever, Familial - Periodic Disease - Periodic Disease, Wolff's