Hereditary Autoinflammatory Diseases

**Definition:** Hereditary inflammation conditions, characterized by recurrent episodes of systemic inflammation. Common symptoms include recurrent fever, rash, arthritis, fatigue, and secondary AMYLOIDOSIS. Hereditary autoinflammatory diseases are associated with mutations in genes involved in regulation of normal inflammatory process and are not caused by AUTOANTIBODIES, or antigen specific T-LYMPHOCYTES.

**Tree numbers:** - C16.320.382 - C17.800.827.368

**Synonyms:** - Hereditary Autoinflammation Diseases - Hereditary Recurrent Fevers - Hereditary Periodic Fever Syndromes - Reimann Periodic Disease - Siegal-Cattan-Mamou Disease