HLA-B Antigens

**Definition:** Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.

**Tree numbers:** - D09.400.430.890.489.500 - D12.776.395.550.489.500 - D12.776.543.550.439.500 - D23.050.301.500.100.500 - D23.050.301.500.450.380 - D23.050.705.552.100.500 - D23.050.705.552.450.380

**Synonyms:** - HLA-B Antigen - HLA-B - Antigens, HLA-B