Deoxyribonucleases, Type II Site-Specific

**Definition:** Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.

**Tree numbers:** - D08.811.150.280.260 - D08.811.277.352.335.350.300.260 - D08.811.277.352.355.325.300.260

**Synonyms:** - Deoxyribonucleases, Type II, Site-Specific - Type II Site Specific Deoxyribonucleases - Type II Site-Specific Deoxyribonucleases - DNA Restriction Enzymes, Type II - DNase, Site Specific, Type II - Site-Specific DNase, Type II - Type II Site Specific DNase - Type II Site-Specific DNase - DNase, Site-Specific, Type II - Restriction Endonucleases, Type II - Deoxyribonucleases, Type II, Site Specific - Type II Restriction Enzymes