CD4 Antigens

**Definition:** 55-kDa antigens found on HELPER-INDUCER T-LYMPHOCYTES and on a variety of other immune cell types. They are members of the immunoglobulin supergene family and are implicated as associative recognition elements in MAJOR HISTOCOMPATIBILITY COMPLEX class II-restricted immune responses. On T-lymphocytes they define the helper/inducer subset. T4 antigens also serve as INTERLEUKIN-15 receptors and bind to the HIV receptors, binding directly to the HIV ENVELOPE PROTEIN GP120.

**Tree numbers:** - D12.776.543.750.705.852.420.810.500 - D12.776.543.750.830.700.025 - D23.050.301.264.894.100 - D23.101.100.894.100

**Synonyms:** - Receptors, CD4 - Surface CD4 Receptor - Receptors, Surface CD4 - T4 Antigens, T-Cell - CD4 Receptor - CD4 Antigen - Antigens, CD4 - CD4 Receptors - CD4 Molecule