Leukotriene C4

**Definition:** The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)

**Tree numbers:** - D10.251.355.255.100.450.855.455 - D10.251.355.310.166.887.855.455 - D23.469.050.175.450.725.400

**Synonyms:** - Leukotriene C-4 - LTC4