SRS-A

**Definition:** A group of LEUKOTRIENES; (LTC4; LTD4; and LTE4) that is the major mediator of BRONCHOCONSTRICTION; HYPERSENSITIVITY; and other allergic reactions. Earlier studies described a slow-reacting substance of ANAPHYLAXIS released from lung by cobra venom or after anaphylactic shock. The relationship between SRS-A leukotrienes was established by UV which showed the presence of the conjugated triene. (From Merck Index, 11th ed)

**Tree numbers:** - D10.251.355.255.100.450.855 - D10.251.355.310.166.887.855 - D23.469.050.175.450.725

**Synonyms:** - Slow Reacting Substance of Anaphylaxis