Leukotriene D4

**Definition:** One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990)

**Tree numbers:** - D10.251.355.255.100.450.855.461 - D10.251.355.310.166.887.855.461 - D23.469.050.175.450.725.415

**Synonyms:** - LTD4 - Leukotriene D-4