src-Family Kinases

**Definition:** A PROTEIN-TYROSINE KINASE family that was originally identified by homology to the Rous sarcoma virus ONCOGENE PROTEIN PP60(V-SRC). They interact with a variety of cell-surface receptors and participate in intracellular signal transduction pathways. Oncogenic forms of src-family kinases can occur through altered regulation or expression of the endogenous protein and by virally encoded src (v-src) genes.

**Tree numbers:** - D08.811.913.696.620.682.725.800 - D12.776.476.568.800

**Synonyms:** - src-Family Kinase - src Kinase - src Tyrosine Kinase - src-Family Tyrosine Kinase - src-Family Tyrosine Kinases - src Kinases - Protein-Tyrosine Kinases, src - Src Family Tyrosine Kinase - src Tyrosine Kinases