Lymphocyte Specific Protein Tyrosine Kinase p56(lck)

**Definition:** This enzyme is a lymphoid-specific src family tyrosine kinase that is critical for T-cell development and activation. Lck is associated with the cytoplasmic domains of CD4, CD8 and the beta-chain of the IL-2 receptor, and is thought to be involved in the earliest steps of TCR-mediated T-cell activation.

**Tree numbers:** - D08.811.913.696.620.682.725.800.315 - D12.776.476.568.800.315 - D12.776.624.664.700.128

**Synonyms:** - Proto-Oncogene Protein c-lck - p56 lck - Protein Tyrosine Kinase p56(lck) - lck Kinase - Proto-Oncogene Protein lck