Genes, p16

**Definition:** Tumor suppressor genes located on human chromosome 9 in the region 9p21. This gene is either deleted or mutated in a wide range of malignancies. (From Segen, Current Med Talk, 1995) Two alternatively spliced gene products are encoded by p16: CYCLIN-DEPENDENT KINASE INHIBITOR P16 and TUMOR SUPPRESSOR PROTEIN P14ARF.

**Tree numbers:** - G05.360.340.024.340.375.249.375 - G05.360.340.024.340.415.400.375

**Synonyms:** - Genes, p16INK4 - p16INK4 Genes - Genes, p16INK4A - CDKN2 Genes - Genes, CDKN2 - Genes, CDKN2A - Genes, MTS1 - p16 Genes - MTS1 Genes