Genes, Tumor Suppressor

**Definition:** Genes that inhibit expression of the tumorigenic phenotype. They are normally involved in holding cellular growth in check. When tumor suppressor genes are inactivated or lost, a barrier to normal proliferation is removed and unregulated growth is possible.

**Tree numbers:** - G05.360.340.024.340.375.249 - G05.360.340.024.340.415.400

**Synonyms:** - Antioncogenes - Emerogenes - Genes, Onco-Suppressor - Tumor Suppressor Genes - Oncogenes, Recessive - Anti-Oncogenes - Tumor Suppressing Genes - Genes, Cancer Suppressor - Cancer Suppressor Genes