Mitogen-Activated Protein Kinases

**Definition:** A superfamily of PROTEIN SERINE-THREONINE KINASES that are activated by diverse stimuli via protein kinase cascades. They are the final components of the cascades, activated by phosphorylation by MITOGEN-ACTIVATED PROTEIN KINASE KINASES, which in turn are activated by mitogen-activated protein kinase kinase kinases (MAP KINASE KINASE KINASES).

**Tree numbers:** - D08.811.913.696.620.682.700.567 - D12.776.476.563.567

**Synonyms:** - Mitogen Activated Protein Kinase - Mitogen-Activated Protein Kinase