JNK Mitogen-Activated Protein Kinases

**Definition:** A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION.

**Tree numbers:** - D08.811.913.696.620.682.700.567.374 - D12.776.476.563.567.374

**Synonyms:** - jun-NH2-Terminal Kinase - c-jun N-Terminal Kinase - jun-NH2-Terminal Kinases - jun N-Terminal Kinase - c-jun Amino-Terminal Kinase