Leukocyte L1 Antigen Complex

**Definition:** A member of the S-100 protein family that is present at high levels in the blood and interstitial fluid in several infectious, inflammatory, and malignant disorders, including rheumatoid arthritis, inflammatory bowel disease, and cystic fibrosis. It is a complex of a light chain (CALGRANULIN A) and a heavy chain (CALGRANULIN B). L1 binds calcium through an EF-hand motif, and has been shown to possess antimicrobial activity.

**Tree numbers:** - D12.776.157.125.750.500 - D12.776.631.658.750 - D23.050.301.562

**Synonyms:** - 27E10 Antigen - Calcium-Binding Myeloid Protein P8,14 - Calgranulin - Calprotectin - Leukocyte L1 Protein - Migratory Inhibitory Factor-Related Protein MRP - Myelomonocytic Antigen L1 - L1 Antigen