Calgranulin A

**Definition:** A 10.8-kDa member of the S-100 family of calcium-binding proteins that can form homo- or heterocomplexes with CALGRANULIN B and a variety of other proteins. The calgranulin A/B heterodimer is known as LEUKOCYTE L1 ANTIGEN COMPLEX. Calgranulin A is found in many cell types including GRANULOCYTES; KERATINOCYTES; and myelomonocytes, and has been shown to act as a chemotactic substance for NEUTROPHILS. Because it is present in acute inflammation but absent in chronic inflammation, it is a useful biological marker for a number of pathological conditions.

**Tree numbers:** - D12.776.157.125.750.500.100 - D12.776.631.658.750.500 - D23.050.301.562.100

**Synonyms:** - Cystic Fibrosis Antigen - 60B8-B Antigen - CABP-P8 - MRP8 Protein - Macrophage-Related Protein-8 - Myeloid Calcium-Binding Protein P8 - MRP-8 Protein - S100 A8 Protein - S100A8 Protein - Leukocyte L1 Protein Light Chain