11-beta-Hydroxysteroid Dehydrogenases

**Definition:** Hydroxysteroid dehydrogenases that catalyzes the reversible conversion of CORTISOL to the inactive metabolite CORTISONE. Enzymes in this class can utilize either NAD or NADP as cofactors.

**Tree numbers:** - D08.811.682.047.436.174 - D08.811.682.047.820.100

**Synonyms:** - Cortisone 11-Oxoreductase - 11beta-Hydroxysteroid Dehydrogenase - 11-Hydroxysteroid Dehydrogenase - 11B-Hydroxysteroid Dehydrogenase - 11 beta-Hydroxysteroid Dehydrogenase - Corticosteroid 11-Reductase - Corticosteroid 11-Oxidoreductase