F-Box Proteins

**Definition:** A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in the process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS.

**Tree numbers:** - D12.776.157.169

**Synonyms:** - F-Box Protein - F-Box Protein Family - F-Box Domain Protein