beta-Transducin Repeat-Containing Proteins

**Definition:** A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.

**Tree numbers:** - D12.776.157.169.500

**Synonyms:** - beta-TrCP - betaTrCP - beta-Transducin Repeat-Containing Protein