Core Binding Factors

**Definition:** Heterodimeric transcription factors containing a DNA-binding alpha subunits, (CORE BINDING FACTOR ALPHA SUBUNITS), along with a non-DNA-binding beta subunits, CORE BINDING FACTOR BETA SUBUNIT. Core Binding Factor regulates GENETIC TRANSCRIPTION of a variety of GENES involved primarily in CELL DIFFERENTIATION and CELL CYCLE progression.

**Tree numbers:** - D12.776.930.155

**Synonyms:** - Core-Binding Factor - PEBP2 Transcription Factor - Polyomavirus Enhancer Binding Protein 2