E2F6 Transcription Factor

**Definition:** An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.

**Tree numbers:** - D12.776.930.211.937

**Synonyms:** - Transcription Factor E2F-6 - E2F Transcription Factor 6 Protein