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D050759Level 6

Cyclin-Dependent Kinase Inhibitor p21

**Definition:** A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.

**Tree numbers:** - D12.644.360.225.500 - D12.776.157.687.250 - D12.776.167.187.500 - D12.776.476.225.500 - D12.776.624.776.355.500 - D12.776.660.720.250

**Synonyms:** - CDK2-Associated Protein 20 kDa - CDKN1 Protein - Senescent Cell-Derived Inhibitor Protein 1 - Cell Cycle Regulator p21 - p21 Cell Cycle Regulator - Cyclin Kinase Inhibitor p21 - p21 Cyclin Kinase Inhibitor - CDKN1A Protein - Cdk-Interacting Protein 1 - Cdk2 Inhibitor Protein - Cyclin-Dependent Kinase Inhibitor 1A Protein

GET/api/v1/systems/mesh/nodes/D050759
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