Cyclin-Dependent Kinase Inhibitor Proteins

**Definition:** A group of cell cycle proteins that negatively regulate the activity of CYCLIN/CYCLIN-DEPENDENT KINASE complexes. They inhibit CELL CYCLE progression and help control CELL PROLIFERATION following GENOTOXIC STRESS as well as during CELL DIFFERENTIATION.

**Tree numbers:** - D12.644.360.225 - D12.776.167.187 - D12.776.476.225 - D12.776.624.776.355

**Synonyms:** - Cyclin-Kinase Inhibitor Proteins - CKI Proteins - CDKI Proteins