Interferon Regulatory Factors

**Definition:** A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.

**Tree numbers:** - D12.644.360.024.302 - D12.776.157.057.050 - D12.776.260.504 - D12.776.476.024.385 - D12.776.930.332

**Synonyms:** - Interferon Regulatory Factor - IRF Transcription Factors