D050916Level 8
TRPV Cation Channels
**Definition:** A subgroup of TRP cation channels named after the vanilloid receptor. They are very sensitive to TEMPERATURE; hot spicy food, and CAPSAICIN. They contain a TRP domain (a five-turn amphipathic helix with an invariant TRYPTOPHAN) and ANKYRIN repeats. Selectivity for CALCIUM over SODIUM ranges from 3 to 100 fold.
**Tree numbers:** - D12.776.157.530.400.901.888
**Synonyms:** - Capsaicin Receptor - Vanilloid Receptor - Capsaicin Receptors - Vanilloid Receptors
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