Inhibitor of Apoptosis Proteins

**Definition:** A conserved class of proteins that control APOPTOSIS in both VERTEBRATES and INVERTEBRATES. IAP proteins interact with and inhibit CASPASES, and they function as ANTI-APOPTOTIC PROTEINS. The protein class is defined by an approximately 80-amino acid motif called the baculoviral inhibitor of apoptosis repeat; some members have ubiquitin-protein ligase activity.

**Tree numbers:** - D08.811.464.938.750.210 - D12.644.360.075.437 - D12.776.476.075.437

**Synonyms:** - Inhibitor-Of-Apoptosis Protein - IAP Protein (Apoptosis) - Baculoviral Inhibitor Of Apoptosis Repeat Proteins - IAP Repeat Containing Proteins