Ubiquitin-Protein Ligases

**Definition:** A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.

**Tree numbers:** - D08.811.464.938.750

**Synonyms:** - Ubiquitin Ligase E3 - Ubiquitin-Protein Ligase E3 - Ubiquitin-Protein Ligase - E3 Ubiquitin Ligase - E3 Ligase