Proto-Oncogene Proteins c-mdm2

**Definition:** An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.

**Tree numbers:** - D08.811.464.938.750.562 - D12.776.624.664.700.185 - D12.776.660.764

**Synonyms:** - Mdm2 Protein - Double Minute 2 Protein - Mdm-2 Protein - Murine Double Minute 2 Protein - c-mdm2 Proto-Oncogene Protein - MDMX Protein